For use during surgical and other procedures and in intensive care to relax skeletal muscles, and to facilitate tracheal intubation and mechanical ventilation. It is used as an adjunct to general anaesthesia, or sedation in the intensive care unit.

For the treatment of serious infections cause by susceptible strains of the following pathogens:

Pseudomonas aeruginosa, Proteus species (indole positive and indole negative), Escherichia coli, Klebsiella, Enterobacter and Serratia species and Staphylococcus species (coagulase positive and coagulase negative).

Gentamicin solution for injection may be used for the treatment of the following conditions when caused by susceptible organisms:

• Septicaemia,
• Respiratory tract infections,
• Infected wounds, bone and soft tissue infections including peritonitis, septic abortion and burns complicated by sepsis
• Urinary tract infections (recurrent, complicated). Gentamicin injection is not routinely indicated in the initial treatment of uncomplicated urinary tract infections unless the organism is resistant to other less toxic antibacterials

Gentamicin solution for injection may be considered as initial therapy in suspected or confirmed gram negative infections. If anaerobic organisms are suspected, additional antimicrobial therapy should be added to the gentamicin regime. The decision to continue therapy with gentamicin should be based on the results of susceptibility tests, the severity of the infection, and the important additional considerations outlined in the SPECIAL WARNINGS AND PRECAUTIONS FOR USE section of the Australian PI. If the causative organisms are resistant to gentamicin and the patient is not responding favourably, other appropriate therapy should be instituted.

Depression: Fluoxetine is indicated for the treatment of the symptoms of depressive illness, with or without associated anxiety symptoms, especially where sedation is not required.

Obsessive-compulsive disorder.

Bulimia nervosa: Fluoxetine is indicated for the reduction of binge-eating and purging activity.

Pre-menstrual Dysphoric Disorder (PMDD)

Diagnosis of PMDD: The essential diagnostic features of PMDD are clear and established cyclicity (occurring during the last week of the luteal phase in most menstrual cycles) of symptoms such as depressed mood, anxiety, affective lability, accompanied by impairment in social and/or occupational function and physical symptoms (such as breast tenderness or swelling, headaches, joint or muscle pain, a sensation of bloating, weight gain) - all of which must be severe. This syndrome should be distinguished from the commoner 'pre-menstrual tension (distinguished from PMDD by milder symptoms and less impact on normal activities)' and from any co-existing psychiatric disorder.

Prevention of vascular ischaemia associated with atherothrombotic events (myocardial infarction, stroke and vascular death) in patients with history of symptomatic atherosclerotic disease.

Acute Coronary Syndrome

Clopidogrel is indicated in combination with aspirin for patients with:

• Unstable angina or non-ST-elevation myocardial infarction in order to prevent early and long-term atherothrombotic events (myocardial infarction, stroke, vascular death or refractory ischaemia)